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Olympus BX51 Fluorescence Microscope
Product Overview
The Olympus BX51 is a professional research-grade microscope designed for transmitted light and fluorescence imaging. It is one of Olympus’ classic and widely trusted platforms, used in research and clinical laboratories around the world.
The BX51 is extensively applied in cell and molecular biology, genetics, pathology, cytogenetics, microbiology, medical research, and academic or diagnostic laboratories.
This system enables users to observe natural cellular structures under brightfield illumination, as well as to precisely detect and image fluorescently labeled molecules and genetic targets with high clarity and resolution.
Modular and Professional Design
The Olympus BX51 features a fully modular design, allowing the system to be configured according to specific user needs. It can be upgraded with various components without replacing the entire microscope, making it suitable for both advanced educational use and high-level research applications.
Key components such as light sources, fluorescence filter sets, cameras, and imaging software can be added or upgraded over time.
Fluorescence Filter Sets (Channels)
The BX51 supports multiple fluorescence filter cubes (typically 3 to 6 positions in the filter turret), enabling multi-channel fluorescence imaging.
Common filter sets include:
DAPI (Blue) – for nuclear staining
FITC / GFP (Green)
TRITC / Cy3 (Orange-Red)
Texas Red
Cy5 / Alexa Fluor 647
Specialized filters for CFP and YFP
🔹 These filters allow simultaneous detection of multiple molecular targets within a single sample.
Light Sources
The BX51 can be equipped with various light sources depending on application requirements:
For Brightfield Imaging:
Halogen lamp with adjustable intensity
For Fluorescence Imaging:
Mercury lamps
Metal halide light sources
Xenon lamps
LED-based fluorescence illumination systems
This flexibility ensures reliable excitation across a wide spectral range, from DAPI to Cy5.
Special Application: FISH (Fluorescence In Situ Hybridization)
One of the key applications of the Olympus BX51 is in FISH (Fluorescence In Situ Hybridization) analysis.
In FISH, fluorescent probes are used to detect and localize specific DNA or RNA sequences within cells or chromosomes.
Thanks to:
High-performance Olympus optics
Precise fluorescence filter sets
Excellent contrast and sensitivity
Multi-channel imaging capability
the BX51 is an ideal platform for FISH applications such as:
Cytogenetic analysis
Detection of chromosomal abnormalities
Cancer diagnostics
Genetic mutation studies
Infertility and IVF testing
Key Features
1. Multi-Channel Fluorescence Imaging
Simultaneous visualization of multiple fluorescent probes in a single specimen.
2. Digital Camera & Computer Connectivity
Compatible with CCD and CMOS cameras for:
High-resolution image capture
FISH result documentation
Quantitative image analysis using software such as ImageJ and cellSens
3. Superior Optical Quality
Equipped with Olympus high-performance objectives delivering:
Exceptional resolution
High contrast
Accurate color reproduction
4. Fully Upgradeable Platform
Expandable with:
Additional fluorescence filters
Advanced light sources
High-sensitivity imaging systems
Applications
FISH and cytogenetics
Cell and molecular biology
Medical genetics
Pathology and histology
Cancer research
Diagnostic and research laboratories
This version is written in scientific marketing style and is fully suitable for:
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